State Street XLV vs. iShares IXJ: Here's How These Healthcare ETFs Stack Up for Investors

Key Points XLV has a significantly lower expense ratio of 0.08% compared to IXJ's 0.38%. IXJ provides broader exposure with 110 holdings across global markets, while XLV concentrates on 60 domestic S&P 500 stocks. XLV has delivered higher one- and five-year total returns compared to IXJ. 10 stocks we like better than iShares Trust - iShares Global Healthcare ETF › Choosing among healthcare funds often comes down to the desired geographic scope and the entry price.