Key Points VHT offers significantly lower ownership costs, with a 0.09% expense ratio compared to XBI's 0.35%. XBI provides targeted focus on biotechnology, while VHT offers exposure to the entire healthcare sector. VHT has demonstrated lower price volatility and a much milder maximum drawdown over the last five years. 10 stocks we like better than Vanguard World Fund - Vanguard Health Care ETF › The Vanguard Health Care ETF (NYSEMKT:VHT) offers broad sector exposure and lower fees, while the State Street SPDR S&P Biotech ETF (NYSEMKT:XBI) provides a concentrated, more volatile play on the biotechnology subsector. Investors looking for exposure to the medical field often weigh broad sector coverage against niche industry plays.
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