Key Points Sandisk was the best-performing stock in the S&P 500 in 2025, and it has advanced 695% in 2026 amid demand for AI infrastructure. In the last decade, the best-performing S&P 500 stock in each calendar year returned a median of 91% during the following year. Sandisk's revenue is growing quickly due to a severe memory chip shortage, not because it has a durable competitive advantage. 10 stocks we like better than Sandisk › Last year, semiconductor company Sandisk (NASDAQ:SNDK) was the best-performing stock in the S&P 500 (SNPINDEX:^GSPC) . Historically, stocks that have claimed that title have often recorded strong returns in the following year.
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